Resistência a drogas, Resistência microbiana, Microbiana
Abstract
Introduction: Antimicrobials are drugs of natural or synthetic origin, they can be classified as bactericidal, when they cause the death of the bacterium, or bacteriostatic, when they promote the inhibition of microbial growth. Antibiotic resistance refers to those microorganisms whose growth and multiplication are not inhibited by the concentrations usually reached in the blood or tissues. Objectives: Analyze bacterial resistance caused by the indiscriminate use of antimicrobials. Methods: The most relevant studies were analyzed, having as reference the database MedLine (National Library of Medicine) and SciELO. In order to select the studies with the greatest scientific evidence, only clinical trials and observational studies were selected. Results: Initially, 121 studies were identified that investigated the association of bacterial resistance due to the indiscriminate use of antimicrobials. However, after applying the inclusion and exclusion criteria, only five were part of the scope of this review. Conclusion: Bacterial resistance to antimicrobials represents a serious threat to global public health, due to abusive and often unnecessary use. For these habits to change, it is important to promote health education for health professionals and for the population, thus avoiding self-medication and promoting their correct use.